Leveraging CRISPR/Cas9 and HDR to create an engineered CD33 CAR-T to target AML […]
Read More… from Keystone Symposia – 2024 – Poster Presentation 2538
Leveraging CRISPR/Cas9 and HDR to create an engineered CD33 CAR-T to target AML […]
Read More… from Keystone Symposia – 2024 – Poster Presentation 2538
Phase 1/2 Study of Donor-Derived Anti-CD33 Chimeric Antigen Receptor Expressing T Cells (VCAR33) in Patients with Relapsed or Refractory Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation […]
CD33-Deleted Hematopoietic Cells (Trem-Cel) Are Protected from CD33xCD3 Bispecific Antibody Treatment and Produce Significantly Reduced Levels of Inflammatory Cytokines in Preclinical Studies […]
Novel CLL-1-directed CAR-T cells Mediate Potent Antigen-specific Cytolytic Activity in Mouse Models of Acute Myeloid Leukemia […]
GUMM: A Purpose-Built Computational Workflow for Single Cell Genotyping of Gene Editing Experiments […]
A Single Cell DNA Sequencing Resource and Computational Approach to Quantify CRISPR-Cas9 Gene Editing Allelism […]
Read More… from Cold Spring Harbor Lab Meeting – 2023 – Poster Presentation P203
CD33-Deleted Hematopoietic Stem and Progenitor Cells Display Normal Engraftment after Hematopoietic Cell Transplant (HCT) and Tolerate Post-HCT GemtuzumabOzogamicin(GO) Without Cytopenias […]